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Destiny 2: Best Grenade Launchers for PvE, PvP, Gambit (2022)

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Destiny 2: Best Grenade Launchers for PvE, PvP, Gambit (2022)

Grenade launchers are in a weird spot nowadays. The nerf hammer finally came for Anarchy and Rocket Launchers have seen a massive buff. Still, there are situations that call for a grenade launcher. Let’s look at the best grenade launchers in Destiny 2 2022 for PvE, PvP, and Gambit as of Destiny 2: Beyond Light.

Best Grenade Launchers in Destiny 2 (2022)

Best in PvE & Gambit

best destiny 2 grenade launchers
  • Deafening Whisper (Energy, Void) – Possible reward from Wrathborn Hunts.
  • Interference VI (Power, Arc) – Random world drop.
  • Ignition Code (Kinetic) – Possible drop from Key Code chests in Override & Splicer Umbral Engrams.
  • Outrageous Fortune (Power, Solar) – Random world drop.
  • Salvager’s Salvo (Energy, Arc) – Ritual weapon quest from Banshee-44.
  • Truthteller (Energy, Void) – Random world drop.
  • Witherhorde (Kinetic, Exotic) – Season of Arrivals seasonal pass reward.

Grenade launchers are a decent PvE option and great for burning down anything tanky, or even taking out hordes of enemies depending on which ones you use.

Any legendary grenade launcher with Spike Grenades and something like Full Court and Auto-loading Holster is going to be decent burst damage weapon on a boss. If you want Spike Grenades are less of a requirement and you can just pick stuff that makes the blast radius bigger. Just shoot it into a group of enemies and watch them go boom.

Anarchy took a massive hit and is no longer the king of sustained DPS. That crown has been taken by Witherhorde, which still stands out as one of the best weapons in the game, and certainly among the best grenade launchers.

Witherhorde is a great hybrid weapon that can be effective both against groups of enemies and also do excellent boss damage as well. Stick a Witherhorde shot onto a boss, and then switch to another weapon and watch the damage ramp up.

Ignition Code has appeared in Season of the Splicer and adds a new kinetic option for those that miss power-relevant Mountaintop, and can roll with random rolls. If you want a similar experience in the energy slot, then Salvager’s Salvo would be the play there. Or heck, run with both and Anarchy in that power slot if you’re a manaic.

Finally, the wave frame launchers have a space now as an excellent add clearing weapon. In particular, Deafening Whisper can roll with Ambitious Assassin which allows you to potentially fire two wave rounds before having to reload if you get enough kills.

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