Fallout 76: How to Get Mutations & What They Do

How to Get Mutations in Fallout 76 and What They Do

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Here’s everything you need to know about how to get Mutations in Fallout 76 and what they do.

As you explore the wasteland in Fallout 76, you’ll come across a variety of different places, most of which have their own threats. Whether that be other players, with Fallout 76 adopting an online multiplayer structure, or environmental issues, they can all be dangerous.

Mutations can be one of the side effects of being too adventurous, and you’ll want to know what they do.

How to Get Mutations & What They Do

You get mutations in Fallout 76 from radiation. Whenever you forget to stock any RadAways on your adventure and take radiation damage, whether that be from irradiated areas or items, you have a chance of getting a mutation.

You won’t get mutations if you are below level 5 though and you can see the effects of any mutations you have by opening the Pip-Boy and going to Stat, and then Effects.

Mutations in Fallout 76 do a few different things. They can have positive effects, such as increased weapon damage or faster health regeneration. However, they can also be negative, such as taking more damage from enemies.

Serums are consumable items that will grant a specific Mutation as soon as you use it. If you already have that Mutation, the Serum will temporarily suppress the negative effects of the mutation and increase the positive effects.

All Mutations We’ve Found So Far

  • Adrenal Reaction – +Weapon DMG and quick health regen at low HP, but Max HP -50
  • Bird Bones – AGI +8, fall from heights is more gradual, but STR -4
  • Carnivore – Meat provides x2 benefit and no disease, but cannot eat vegetables
  • Chameleon – Invisibility while crouched, unarmored, and standing still
  • Eagle Eyes – Critical Damage +25%, PER +4, but STR -4
  • Egg Head – INT +6, STR -3, but END -3
  • Electrically Charged – Chance to shock melee attackers
  • Empath – Damage taken by teammates -25%, but damage you take +33%

You can also check out the full list of every mutation we have found so far.

How to Get Rid of Mutations

Mutations in Fallout 76 are semi-permanent. Every time you use RadAway, there is a chance that the Mutation will be removed. You can keep using RadAway for more attempts to remove a Mutation if you’re intent of getting rid of it.

As you’ll see from the full list of Mutations we’ve found so far, some of them are good and some of them are bad. Most of them tend to have positive effects, but some will also come with a negative effect so it’s whether or not you deem the positive to outweigh the negative.

Also, the perk card Starched Genes prevents you from gaining new ones but also stops your mutations from getting removed by RadAway.

That’s all there is to know about how to get mutations in Fallout 76. For more tips and tricks on the game, check out our Fallout 76 wiki guide, or some other guides below.


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Tom Hopkins
Having been Editor on multiple sites, Tom has a wealth of video game knowledge and is now Managing Editor at Twinfinite. He's an expert on Call of Duty, sports games, PlayStation exclusives, and blockbuster action games. If he's not playing the new release, he'll be grinding on EA FC 24.