SPOILERS AHEAD
If you’ve been playing Metal Gear Solid V: The Phantom Pain, then you may have noticed that this game contains a lot of content. So much content that a large chunk of it may never be seen, except by the most vigilant of players. One of piece of content that is definitely not for the faint of heart is Mission 46.
For those who have already “beaten” Metal Gear Solid V: The Phantom Pain, the noticeable gap between Mission 44 and 47 must be eating away at you. It turns out that this isn’t a mistake, since there are in fact a Mission 45 and 46, they just takes a helluva lot of effort to unlock.
While difficult to obtain, Mission 45 is the much easier of the two. But before you can even consider unlocking it, there are a few requirements that absolutely need to be met. You must have recruited Quiet, max out your bond with her, spare her at the end of Mission 11, and have the scientist exiled from Mother Base. This will unlock Side Op 150 for play. Enter and complete Side Op 150, and Mission 45 will begin immediately at the end of that. Complete Mission 45, and you can now begin the process of unlocking mission 46.