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mass effect 2 all main missions

Mass Effect 2: All Main Missions List

Mass Effect 2 contains many side missions that you wouldn’t want to skip, but what if you wanted the quickest route to the end of the game? We’ve got you covered, whether you’re a newcomer or a returning longtime fan. Here’s a list of all of the main missions in Mass Effect 2.

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Spoiler Warning: Please keep in mind that the names of some of the main missions can hint at some of the story beats in Mass Effect 2

All Main Missions in Mass Effect 2

Mass Effect 2 allows players to complete many of its missions in whatever order they see fit, much like in Mass Effect 1. The following list of missions takes this into account by listing them in the general order that they appear in the story. The game is split up into three acts and several sections. Each section contains a number of individual missions to complete. That includes the highly recommended loyalty missions, even though they’re technically optional.

  1. Prologue
    • Save Joker
    • Awakening
    • Freedom’s Progress
  2. Stop the Collectors: Assemble a Team
    • Dossier: Archangel
    • Dossier: The Professor
    • Omega: Aria T’Loak
    • Dossier: The Convict
    • Dossier: The Warlord
    • Dossier: The Veteran
    • Dossier: The Master Thief
  3. Stop the Collectors: Go to Horizon
    • Horizon
  4. Stop the Collectors: Assemble a Team II
    • Dossier: Tali
    • Dossier: The Assassin
    • Dossier: The Justicar
  5. Stop the Collectors: Investigate Collector Ship
    • Collector Ship
  6. Loyalty Missions (Optional But Recommended)
    • Miranda: The Prodigal
    • Jack: Subject Zero
    • Garrus: Eye for an Eye
    • Mordin: Old Blood
    • Jacob: The Gift of Greatness
    • Tali: Treason
    • Grunt: Rite of Passage
    • Thane: Sins of the Father
    • Samara: The Ardat-Yakshi
  7. Stop the Collectors: Acquire Reaper IFF
    • Reaper IFF
  8. Stop the Collectors: Await IFF Installation
    • Legion: A House Divided
  9. The Suicide Mission (POINT OF NO RETURN)
    • Use Omega-4 Relay
    • Collector Base: Infiltration
    • Collector Base: The Long Walk

And that’s the list of every single main mission in Mass Effect 2. If you’re looking for more tips, tricks, or other general info, check out our guide wiki for Mass Effect Legendary Edition. You can also have a look at our other Mass Effect coverage in the related articles below.


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Ethan Anderson
Ethan was formerly Deputy Guides Editor at Twinfinite, having worked at the site from 2019 to 2022. A lover of anime, RPGs and all things Genshin Impact, Apex Legends, Zelda, Pokémon, Dragon Age, or Tales related. He can usually be found either struggling/failing to get 100% completions, or praying for a Jak 4.