Be Aware of Your Partner’s Abilities
As stated in the beginning of the game, both Billy and Rebecca have their own unique skillsets. Rebecca can mix herbs, but Billy can move heavy objects. You’ll also need to be aware of whether your partner is in ‘Team’ or ‘Solo’ mode. If you select ‘Solo’ mode, your partner will act independently of you. On the other hand, ‘Team’ mode will allow your partner to stick with you at all times.
Another good thing to note is that if you exit a room while in ‘Team’ mode, your partner will automatically join you in the next area even if he or she was all the way at the other end of the room for some reason. The only exception to this is if your partner was under attack by a zombie. In which case, you’ll have to save your partner from danger or risk getting a Game Over if he or she dies.
That said, the AI in Resident Evil 0 is surprisingly solid, so you really only have to worry about their safety if they happen to be low on health.