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Other weapons that will get the job done include any heavy weapons such as the Fat Man, or other missile launchers and nukes. The Mirelurk Queen is extremely slow so you should be able to get in some accurate shots. Be careful not to get too close to her or she’ll stomp you to death. As long as you keep your distance, you’ll only have to worry about the acid spit and the other Mirelurks she summons.
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