Use the Environment for Cover
While you may not have a shield or any means to defend yourself in the world of Hyper Light Drifter, you can use the environment to your advantage. When you’re struggling to take down enemies because of incoming fire, try and get a part of the environment in between yourself and said incoming fire to protect your health bar. As long as you can reach other enemies with your ranged weapon from behind the cover, you can still thin out the army of foes waiting for you, while keeping your health bar nice and healthy.
This is particularly useful when entering a room with turrets. These things will pop up from the ground as soon as you come into range and pepper you with lethal gunfire. At this point, running into walls and hiding behind them is your best chance of survival as you plan out your route to the next safe point.