Prepare Your Mutagens
Blood and Wine doesn’t just bring a new storyline with it, but a bunch of new gear and features. One of the more interesting ones for those who like to get really deep into the RPG mechanics of The Witcher 3 is Mutations. These allow you to combine Mutagens with Ability Points to add powerful new perks to Geralt, such as the ability to have your Signs cause critical damage.
Therefore, it’s always a good idea to make sure that you’ve not only got the best possible Mutagens available to you (remember, combining smaller Mutagens to make bigger ones boosts their effects), but a couple of spares to throw into this new system, too. This will mean that when you come across the Mutations system in Blood and Wine, you’ll be all set to make the most of these powerful new perks.