Grand Theft Auto: San Andreas
Big Smoke: He might be a huge meme now, but an incredibly painful betrayal to gamers around the globe occurred when San Andreas players discovered the cruel betrayal of Big Smoke.
Along with Ryder, CJ’s lifelong friend Big Smoke betrayed him and the rest of GSF (Grove Street Families), by meeting with the Ballas and C.R.A.S.H, ultimately selling out Groove St to gain money and power.
After Sweet declines his request to sell harder drugs and regain influence as a gang, Melvin Harris (a.k.a Big Smoke) easily gets Ryder on his side, and his desire for fortune and fame causes him to throw all his friends under the bus, becoming a fortified drug lord, with protection from Vargos and the Ballas, and a sugar-coated media persona that shadowed all his criminal antics.
CJ gets his redemption, however, and kills his former friend in a raging gun battle. I mean, he kinda got what was coming to him.