No Paragon and Renegade
Perhaps the biggest change for Andromeda, is the removal of the morality system from the original trilogy known as Paragon and Renegade. Bioware has been vocal about why they removed this, as the system felt like it was ingrained with the Commander Shepard character. They also want players to really think about the choices they’re making, instead of just picking the Paragon or Renegade choice.
This could result in much more meaningful choices for Andromeda, and it’s sure to have some morally challenging moments just like previous games. However, the Paragon and Renegade systems have been a constant part of Mass Effect since the first game, directly playing into the experience. Hopefully, Bioware has found a way to make the absence of this system not seem obvious, or have some new features to put in its place.