William Birkin G4 (Resident Evil 2)
While the Tyrant known as Mr. X was certainly the highlight of Resident Evil 2, following Claire and Leon around nonstop, his actual final boss fight with Leon is a little disappointing. There was someone else that just got better with each encounter though: William Berkin.
Having injected himself with the G-Virus, William Berkin will fight Leon and Claire in many different forms throughout the game.
Once he reaches the G4 state of the mutation against Claire, the fight is taken to a whole new level.
G4 Berkin climbs all over the place, making his movements hard to read and sporadic. As the fight goes on, every eyeball that gets taken out makes it harder to hit the next one.
Combine this with the fact that Claire gets to wield a conveniently placed mini-gun and fans will agree this is Resident Evil at its finest.
