Gym Leader Sabrina
If you ever watched the first season of the Pokemon anime, you know how scary the gym leader Sabrina is. Dubbed the “Mistress of Psychic-type Pokemon,” Sabrina has many unnatural abilities, even for the Pokemon world.
When Sabrina was young, it was discovered she had strong psychic abilities that she began to obsess over. She focused only on perfecting her abilities but, by doing so, neglected her emotions and family.
By the time Ash Ketchum meets her, she has two forms; her regular adult form and a small, child-like doll form. While her adult form is still very much present, the child form does most of the interaction.
When Ash lost his second battle against her, Sabrina changed Brock and Misty into dolls and placed them within her dollhouse. What makes it all the worse is that they were both still conscious while in doll form.
Brock and Misty discovered that Sabrina had transformed her own mother into a doll, all so the child version of herself could play with them.
Ash was only able to get his friends back once his Haunter resurfaced Sabrina’s buried emotions. Pokemon can sometimes get pretty deep, mirroring how some people neglect their emotions/family for work, money, or goals.