Reflexes
The Reflexes ability is a must-have for High Chaos players because of the defensive perks it can give you. Simply purchasing the base ability will allow you to parry attacks, which is great for mitigating incoming damage in Dishonored 2. It’s also worth noting that Reflexes will let you parry ranged attacks as well, so there’s no more need to duck and hide whenever someone comes at you with a gun. If you can parry the bullets, that is.
I highly recommend picking up the Superior Deflect and Adept Parry skills down the line too, especially if you happen to take a liking to the parrying mechanic in the game. Superior Deflect lets you deflect bullets and bolts onto nearby enemies, which is a fantastic skill to have if you’re facing off against multiple ranged opponents. On the other hand, Adept Parry increases your parry window. This means that you’ll have more time and leeway to pull off a successful parry. This is especially useful for beginners or players still trying to get a hang of the mechanic. Considering its low cost (only one rune!), there’s no reason not to get this one.
Lastly, Snap Reaction is another handy ability for High Chaos players. It slows down time whenever you’re spotted by enemies, giving you time to react and counterattack.