The regular mobs are bad enough.
While discussing the various enemy types with Game Informer, Arkane Studios confirmed that the new Prey game will not feature any boss fights of the sort.
‘“We don’t have anything like boss fights in the game, but because of the way the A.I. works, [Telepaths] feel like a miniboss,” Bare says. “He owns an area and typically has a cluster of humans that he’s taken over. The humans are interesting, because they are aware of the fact that they’ve been possessed, so if they see you they’ll say things like, ‘I can’t stop myself. Run, get away. We’re both going to die,’ that kind of thing. That presents the player with an interesting choice. Do I cap this person, but they’re actually a human being, or do I try to find a way to avoid them or take them down nonlethally?”’
That said, the enemy type referred to here (the Telepath) is an interesting foe that should create some gameplay dilemmas for the player. As long as the regular enemies in Prey are unique and challenging enough in their own right, coupled with an intriguing story, the absence of bosses shouldn’t be much of a problem.
Prey is set to be released for the PS4, Xbox One, and PC in 2017.