Infinite Escapes
The UNSC Infinity has been positioned as a vital piece of Halo since showing up in the last game, both in the story and multiplayer modes. It’s where Sarah Palmer and the other Spartan-IVs train and live, and Master Chief and Blue Team directly reported to Infinity before they disappeared at the start of Halo 5. Cortana makes finding and eliminating the ship and its crew a specific mission for her – she proclaims “playtime is over” once she finally tracks them down at the end of the game.
Infinity manages to enter slipspace to escape her wrath, but there’s no way it ends here. Lasky has the ship avoid major settlements until they can find a way to beat Cortana, and it wouldn’t be surprising if this stuck around in the expanded fiction in books and comics down the line. Exactly what it is about them that specifically Cortana wants to get rid of is a mystery; maybe they have something that could lead to her demise, since they ended up in a gravity well on Requiem. It could even just be that their AI Roland has potential in him that she recognizes. Early on, he seemed offended at Lasky and Halsey thinking that Cortana had to die, which could be a warning sign. It could even be something as simple as her not accepting his refusal to join her and wanting to punish him. Whatever the case, the Infinity is the only known ship, UNSC or otherwise, with power. That’s gonna be one goddamned hurdle in the future.